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About TPI

Therapeutic Peptides was founded by Don R. Owen, Ph.D., in 1992, with the mission of designing, testing, synthesizing, and integrating peptides and peptide derivatives into successful formulations for the personal healthcare and pharmaceutical industry.

Based upon experience gained in peptide development and synthesis as a faculty member at Tulane University, Dr. Owen focused TPI’s initial development efforts on cationic amphipathic peptides, offshoots of Dr. Jesse Jaynes’ work at LSU that centered on their antimicrobial properties for wound healing. The research resulted in patents issued to Dr. Owen (US Patents 6,875,744; 7,354,903; and 7,381,704) and later assigned to various companies.   

Subsequently, TPI began work on a next generation of peptides. “We were looking at ways to reduce costs by reducing the size of the peptide, but it became obvious that the antimicrobial properties of the peptides decreased as the number of lysines in the peptide decrease,” Dr. Owen recalls. “We began a development effort to attach lipid tails to shorter (nine to three amino acids) peptides to make bio-surfactants and return antimicrobial activity to the compounds. The resulting lipopeptides had a conventional head-tail relationship, formed micelles, foamed in water, possessed a CMC, and were enzyme digestible. The sequence selections lead to the issuance of US Patents 8,431,523 and 8,586,541, which were assigned to TPI. 

TPI’s ongoing research efforts have yielded a large library of current innovative oligopeptides and lipopeptides that are rigorously tested, validated, and used in commercial applications. Through the association with Owen Biosciences, Inc., TPI substantiates the efficacy of finished formulations and delivery technologies for the cosmeceutical and personal healthcare industries. 

Why Choose TPI

Therapeutic Peptides, Inc. (“TPI”)is a premier developer of peptide and peptide-based bioactive molecules for personal healthcare product applications including anti-aging skin care and hair care as well as oral, eye, and vaginal care. Its patented biosurfactant technology platform provides enhanced metabolic bioactivity and better transdermal delivery at lower costs.   

TPI’s ongoing research efforts have yielded an extensive library of current innovative oligopeptides and lipopeptides that are rigorously tested, validated, and used in commercial applications.   

TPI’s expertise includes assisting its clients in integrating the peptide and lipopeptides into commercial formulations through its affiliate, Owen Biosciences, Inc. (“OBI”). The efficacy of finished formulations and delivery technologies for the cosmeceutical and personal healthcare industries are substantiated and samples of such formulations can be obtained directly from OBI. 

Safe Peptides For All Your Applications

Our Promise

Therapeutic Peptides, Inc. is committed to providing bioactive and safe peptides and peptide derivatives for the cosmeceutical and pharmaceutical industriesTPI’s peptides and peptides derivatives are developed and manufactured in the USATPI has developed in vitro (animal-free) models using the cells found in the skin (keratinocytes, fibroblasts, and melanocytes) and combined with qPCR, viability measurements, microbiological tests, and additional test methods we validate our peptides and peptide derivatives for a wide array of applications. 

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Green Chemistry TPI Track Record

Sustainability

TPI has led the way in investigating food-grade enzyme technology in keeping with green chemistry standards that can produce oligopeptides and lipo-oligopeptides for cosmeceutical and pharmaceutical applications that can be manufactured in large quantities required for use in bioactive cosmetic applications.  

RSPO Certification

In keeping with sustainability TPI’s RSPO (Round Table of Sustainable Palm Oil) certification validates our commitment to our clients to provide sustainable supply chain initiatives.

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Certified Sustainable Palm Oil RSPO 9-4531-22-000-00