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These lipo-oligopeptides share the common property of containing three lysine residues with at least two additional non-charged amino acid residues and may be acid or amide terminated. Trilysyline® peptides possess the common properties of being stimulating to normal human cells yet can lyse bacteria at concentrations that do not inhibit healthy cell activity.

Strengthens Skin, Hair & Lashes

Trilysylines®

Myristoyl Nonapeptide-3 offers comparable activity to retinoic acid but without the skin irritation and sun sensitivity. This peptide can increase cell turnover and promote the synthesis of collagen without inflammation.  

Myristoyl Nonapeptide-3 in products can increase cell turnover and stimulate skin’s natural collagen production mimicking the effects of retinol for a smoother, more youthful complexion without any of the harsh side effects of retinoids. It improves the appearance of fine lines and wrinkles and helps renew and regenerate skin. This leads to an improved barrier function and helps retain skin moisture. 

Can be used in anti-acne creams, cleansers, moisturizers, and eye products. Suitable for most skin types. In one study retinoic acid upregulated 21 of the 92 studied genes, and amongst those, 16 genes were also upregulated by Myristoyl Nonapeptide-3.

Benefits:  Stimulate, Protect, Anti-wrinkle

RetinoPeptide™ 189

P189 Myristoyl Nonapeptide-3

P189 Peptide Chart

P189 stimulates cell proliferation by 22% when added to healthy human skin cells in vitro at 30 ppm.

A five amino acid peptide attached to the oil-soluble, myristic acid for better bioavailability. This benchmark peptide is a superb multitasker via stimulation of skin cell regeneration, antimicrobial activity, reduction in inflammatory compounds, and smoothing skin texture.  

The short cationic structure is recognized to be effective against unwanted bacteria and fungi, like C. acnes and yeast, while enhancing the skin’s natural immune function. With regular use, we see an increase in structural proteins of the epidermis and an increase in the natural defense system of the skin.  

It is known to significantly stimulate keratin genes to direct the cells to produce more keratin, an important structural protein in hair, nails, and the outermost layer of the skin. Myristoyl Pentapeptide-17 is combined with Myristoyl Hexapeptide-16 in many eyelash growth products, as the two together can visibly increase eyelash length after two weeks.

Benefits: Stimulate, Protect, Probiotic, Anti-inflammatory, Anti-wrinkle, Acne Treatment, Hair and Eyelash Growth 

SymPeptide® 226

P226 - Myristoyl Pentapeptide-17

P226 peptide chart

P226 and P235 stimulate keratin production in healthy human skin cells when compared to untreated cells. Cells were treated with 10 ppm in vitro.

Peptide 226 eyelash growth

This hydrophilic peptide is rich in the essential amino acid threonine and made more bioactive by our modifications during production. In vitro studies show collagen IV and VII upregulation, fibronectin, elastin, and integrin upregulation, and MMP-1 downregulation. It improves the skin’s structure and prevents the breakdown of collagen to help strengthen skin. With enhanced penetration capabilities the hydrophilic nature of Myristoyl Hexapeptide-4 promotes hydration and healthy skin balance.

Benefits: Nourish, Hydrate, Anti-wrinkle, Firming

SymPeptide® 230

P230 Myristoyl Hexapeptide-4

P230 Peptide Chart

P230 stimulates the proliferation of healthy human skin cells when compared to untreated cells. Cells were treated with 10 ppm in vitro.

A six amino acid peptide attached to, myristic acid for better bioavailability. It is known to significantly stimulate keratin genes to convince the cells to produce more keratin, the important structural protein in hair, nails, and the outermost layer of the skin. Myristoyl Pentapeptide-17 is combined with Myristoyl Pentapeptide-16 in many eyelash growth products, as the two together can visibly increase eyelash length after two weeks.

Benefits: Stimulate, Protect, Anti-inflammatory, Hair and Eyelash Growth

SymPeptide® P235

P235 Myristoyl Hexapeptide-16

P235 Peptide Chart

P235 stimulates keratin gene expression when added to healthy human skin cells in vitro at 5 ppm.

Myristoyl Hexapeptide-23 is a peptide with a structure that slows enzymatic degradation. Designed for skin permeation and the stimulation of healthy cell turnover. It is antimicrobial without being harsh. Provides antimicrobial and anti-inflammatory properties to aid in acne and problem skin treatments. 

Benefits: Stimulate, Probiotic, Anti-inflammatory, Anti-wrinkle, Acne Treatment

SymPeptide® 380

P380 Myristoyl Hexapeptide-23

P380 Peptide Chart

P380 stimulates the proliferation of human skin fibroblasts by 20 % when compared to untreated cells. At the same concentration, it shows strong antimicrobial activity.

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