These lipo-oligopeptides share a common structural profile that includes three lysine residues and at least two additional non-charged amino acid residues and may be acid- or amide-terminated.
Trilysyline® peptides have been evaluated in laboratory models for their functional characteristics and compatibility with normal human cells. Certain members of this peptide class have also demonstrated activity in microbiological test systems, supporting further research into their potential use in topical formulation development.
Strengthens Skin, Hair & Lashes
Trilysylines®
Myristoyl Nonapeptide-3 is a cosmetic peptide ingredient developed for use in advanced skincare formulations. It has been studied for its ability to support the appearance of smoother, firmer, and more youthful-looking skin.
In topical formulations, Myristoyl Nonapeptide-3 may help improve the appearance of fine lines, wrinkles, texture, hydration, and overall skin quality. It may be incorporated into cleansers, moisturizers, eye products, and other cosmetic skincare formulations suitable for a broad range of skin types.
Laboratory studies have also evaluated Myristoyl Nonapeptide-3 using gene-expression analysis as part of ingredient characterization. In one study, its expression profile overlapped with a subset of genes evaluated in comparison with retinoic acid, providing additional information relevant to cosmetic formulation research.
Benefits: Smooth, Firm, Protect
RetinoPeptide™ 189
P189 Myristoyl Nonapeptide-3
P189 stimulates cell proliferation by 22% when added to healthy human skin cells in vitro at 30 ppm.
Myristoyl Pentapeptide-17 is a five-amino-acid peptide modified with myristic acid to support compatibility with topical formulations. It is used in cosmetic skin, hair, and eyelash care products for its conditioning and appearance-enhancing properties.
In topical applications, Myristoyl Pentapeptide-17 has been studied for its ability to support the appearance of smoother, healthier-looking skin and to improve the overall condition of hair and eyelashes. It may also be incorporated into formulations designed to support skin texture, comfort, and cosmetic performance.
Myristoyl Pentapeptide-17 is often combined with Myristoyl Hexapeptide-16 in eyelash and hair care formulations intended to improve the appearance, condition, and visible fullness of lashes and hair.
Benefits: Skin Conditioning, Smoothing, Appearance of Fine Lines, Hair & Lash Conditioning, Visible Fullness, Formulation Performance, Blemish-Prone Skin Support
SymPeptide® 226
P226 - Myristoyl Pentapeptide-17
P226 and P235 stimulate keratin production in healthy human skin cells when compared to untreated cells. Cells were treated with 10 ppm in vitro.
This hydrophilic peptide is rich in the essential amino acid threonine and made more bioactive by our modifications during production. In vitro studies show collagen IV and VII upregulation, fibronectin, elastin, and integrin upregulation, and MMP-1 downregulation. It improves the skin’s structure and prevents the breakdown of collagen to help strengthen skin. With enhanced penetration capabilities the hydrophilic nature of Myristoyl Hexapeptide-4 promotes hydration and healthy skin balance.
Benefits: Nourish, Hydrate, Anti-wrinkle, Firming
SymPeptide® 230
P230 Myristoyl Hexapeptide-4
P230 stimulates the proliferation of healthy human skin cells when compared to untreated cells. Cells were treated with 10 ppm in vitro.
A six amino acid peptide attached to, myristic acid for better bioavailability. It is known to significantly stimulate keratin genes to convince the cells to produce more keratin, the important structural protein in hair, nails, and the outermost layer of the skin. Myristoyl Pentapeptide-17 is combined with Myristoyl Pentapeptide-16 in many eyelash growth products, as the two together can visibly increase eyelash length after two weeks.
Benefits: Stimulate, Protect, Anti-inflammatory, Hair and Eyelash Growth
SymPeptide® P235
P235 Myristoyl Hexapeptide-16
P235 stimulates keratin gene expression when added to healthy human skin cells in vitro at 5 ppm.
Myristoyl Hexapeptide-23 is a peptide with a structure that slows enzymatic degradation. Designed for skin permeation and the stimulation of healthy cell turnover. It is antimicrobial without being harsh. Provides antimicrobial and anti-inflammatory properties to aid in acne and problem skin treatments.
Benefits: Stimulate, Probiotic, Anti-inflammatory, Anti-wrinkle, Acne Treatment
SymPeptide® 380
P380 Myristoyl Hexapeptide-23
P380 stimulates the proliferation of human skin fibroblasts by 20 % when compared to untreated cells. At the same concentration, it shows strong antimicrobial activity.